MRPL13 缺乏引发热囊细胞线粒体未折叠蛋白质反应在早期发病的孕前症

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Updated: Feb 4, 2026

Trophoblast Cell Recovery from Angiogenesis-Tube Formation Assay for Differentiation Marker Expression Analysis
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Published on: November 8, 2024

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Xiaoxu Chen1, Qinying Zhu1, Wang Liying1

  • 1National Clinical Research Center for Women's Health and Obstetric and Gynecologic Diseases, Department of Obstetrics and Gynecology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College.

Reproduction (Cambridge, England)
|February 3, 2026
PubMed
概括

与减少MRPL13相关的线粒体功能障碍,通过损害热原体细胞功能,加剧了早期发病的孕前. 这项研究强调了MRPL13在线粒体展开蛋白反应 (UPRmt) 中的作用及其对妊娠并发症的影响.

关键词:
早期发病的妊娠前.线粒体功能障碍 线粒体功能障碍线粒体核糖体中的线粒体核糖体胎盘 trofhoblast 是一个胎盘 trofhoblast.不折叠的蛋白质反应反应

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