腰部甘油指数和胆结石之间的关联:一个横截面研究
Hongliang Li1, Congfeng Zhang2
1Department of General Surgery, Dandong Central Hospital, Dandong, China.
Medicine
|February 3, 2026
概括
腰部甘油三指数 (WTI) 与较高的胆结石风险有关. 这种新型的代谢指标显示出识别胆结石患病率的潜力,特别是在特定的年龄和健康群体.
科学领域:
- 代谢健康和疾病流行病学
- 胃肠道健康和疾病
- 生物标志物的发现和验证.
背景情况:
- 腰部甘油三指数 (WTI) 是一种新型的代谢综合征 (MetS) 指标.
- WTI和胆结石之间的关联仍未得到研究.
- 胆结石是一个严重的公共卫生问题,具有复杂的风险因素.
研究的目的:
- 为了研究腰部甘油指数 (WTI) 和胆结石之间的关联.
- 评估WTI与胆结石其他代谢指标相比的预测能力.
- 为了探索WTI-gallstone关系中的潜在子组差异.
主要方法:
- 来自国家健康和营养检查调查 (2017-2020) 数据的分析.
- 包括参与者特征分析,多变量逻辑回归,平滑曲线拟合和子组分析.
- 使用接收器操作特征 (ROC) 曲线来比较WTI与其他标记器的预测能力.
主要成果:
- 总共分析了3752名参与者,胆结石患病率为10.6% (399例).
- 每个单位增加WTI与75%更高的患有胆结石的概率有关 (OR=1.75).
- 与内脏脂肪指数,TyG,腰围,BMI和TG相比,WTI显示出更好的预测能力 (AUC=0.661).
结论:
- 较高的WTI与增加胆结石的几率显著相关.
- WTI显示出作为胆结石疾病的有价值的关联标记物的潜力.
- 这种关联在50岁以下的个体和HbA1c>6.5%的个体中尤其显著.
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