早期风险分层的急性角膜炎使用procalcitonin,CRP和CT成像:一个回顾性分析
Ozan Barış Namdaroğlu1, Ahmet Cem Esmer2, Selen Öztürk1
1Department of General Surgery, University of Health Sciences Türkiye, İzmir Tepecik Education and Research Hospital, İzmir, Türkiye.
Turkish journal of surgery
|February 3, 2026
概括
早期风险分层对膜炎至关重要. 甲和CT扫描有效地识别严重病例,指导治疗并减少轻度膜炎的不必要干预.
科学领域:
- 胃肠病学 胃肠病学
- 手术瘤学手术瘤学
- 医疗成像医学成像
背景情况:
- 区分轻度与严重的分泌炎对于适当的患者管理至关重要.
- 早期风险分层有助于及时和有效的治疗决策.
研究的目的:
- 评估炎症生物标志物和成像特征的预测价值,以评估急性分炎的早期风险分层.
- 为了比较C-反应蛋白 (CRP) 和公素在区分分歧点炎严重性的诊断准确性.
主要方法:
- 对72名患有急性角膜炎的患者 (2017-2024) 的回顾性分析.
- 接收器操作特征 (ROC) 分析,以确定CRP和prokalcitonin的最佳切断值.
- 评估计算机断层扫描 (CT) 发现的诊断能力,以预测疾病严重程度.
主要成果:
- 与CRP (AUC 0.755) 相比,前素显示出更高的预测性能 (AUC 0.795).
- 鉴定出最佳切断值为前素的0.095和CRP的104.5.
- 特定的CT模式,特别是盆腔的局部化,对于严重的分泌体炎具有很高的特异性,在与生物标志物相结合时显著提高了诊断准确性.
结论:
- 采用生物标志物引导的方法,使用前素和有针对性的CT评估,可以可靠地早期识别严重的分炎.
- 这一策略可以增强临床决策的抗生素选择和外科咨询.
- 它还可以减少轻度膜炎患者不必要的干预.
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