定制的出生体重百分值用于SGA短雕像的识别
Corinna Melanie Held1, Andreas Krebs2, Dirk Manfred Olbertz3,4
1Department of Pediatrics and Adolescent Medicine, Schwarzwald-Baar-Klinikum, Villingen-Schwenningen, Germany.
Journal of pediatric endocrinology & metabolism : JPEM
|February 3, 2026
概括
与传统方法相比,定制百分位识别出更小的妊娠年龄 (SGA) 婴儿,但不会增加需要生长激素治疗的持续矮身 (SGA-SS) 的诊断.
科学领域:
- 儿科 儿科 儿科
- 新生儿科学 新生儿科学
- 内分泌学 在内分泌学.
背景情况:
- 10-15%的小于妊娠年龄 (SGA) 儿童发展持续矮身 (SGA-SS),可能受益于生长激素治疗.
- 定制的百分位数,包括母体因素,可以改善对有风险的新生儿的识别.
研究的目的:
- 评估定制的出生体重百分位是否会影响SGA-SS的诊断和随后的治疗决策.
- 为了比较SGA-SS诊断的频率,使用传统和定制百分位定义.
主要方法:
- 分析了1321名婴儿 (妊娠年龄≥30周) 的出生数据,使用传统和定制的出生体重百分比.
- 评估2岁和4岁的生长数据,以确定SGA婴儿持续矮身 (SGA-SS).
主要成果:
- 定制百分位确定了更多的SGA婴儿 (11.9%) 比传统婴儿 (9.8%).
- 41名高体重母亲的婴儿被专门通过定制的百分位数识别出来.
- 在2-4岁的持续矮身 (SGA-SS) 诊断显示,这两种百分位数方法之间的差异很小.
结论:
- 定制百分位增加了基于出生体重的SGA婴儿的分类.
- 这些定制方法似乎没有发现比传统方法更多的产后生长衰竭 (SGA-SS) 病例.
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