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对于静脉瘤的CyberKnife立体辐射手术:长期瘤控制和听力保护结果的系统审查和元分析
Nolan J Brown1, Zach Pennington2, Saarang Patel1
1Department of Neurosurgery, University of California, San Diego, San Diego, California, USA.
Neurosurgery practice
|February 3, 2026
概括
网络刀放射性外科手术 (CKRS) 有效地控制着前庭神经瘤,具有很高的听力保存率,与玛刀放射性外科手术 (GKRS) 相美. 需要进一步的研究来确认这种安全的治疗选择的长期结果和最佳剂量.
科学领域:
- 神经外科 神经外科
- 辐射瘤学 辐射瘤学
- 听力学 听力学是指听力学.
背景情况:
- 立体射线外科手术是小前庭神经瘤的关键治疗方法,特别是在听力受损的患者中.
- 网络刀辐射手术 (CKRS) 和玛刀辐射手术 (GKRS) 是主要的方法,CKRS提供了更高,分量剂量的潜力.
- 最佳CKRS剂量和听力结果需要进一步调查.
研究的目的:
- 系统地审查和元分析前庭神经瘤中CKRS的结果.
- 评估与CKRS相关的瘤控制,听力保护和剂量方案.
- 为了比较CKRS的疗效与现有的治疗方式.
主要方法:
- 我们对PubMed,Scopus和Embase数据库进行了系统的文献搜索.
- 包括回顾性研究,报告CKRS后局部瘤控制和听力保存率.
- 分析按照PRISMA和分析指南进行.
主要成果:
- 分析了包括2018名患者 (1998-2018) 在内的15项研究,平均随访时间为40个月.
- 观察到总体局部控制率为96%和听力保护率为73%.
- 常见的并发症包括面部神经病变 (1.4%) 和三角神经疼痛 (1.3%).
结论:
- CKRS显示出高瘤控制和听力维护率为前庭神经瘤.
- 对于患有小瘤和听力受损的患者来说,CKRS是一种可行的和安全的选择.
- 进一步的大规模研究和与GKRS进行直接比较是有必要的.
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