基于芝加哥分类版本3.0的上胃肠道症状患者食道运动障碍的频率评估
Yorinari Ochiai1,2, Yasutaka Kuribayashi1, Akihiro Yamada1
1Gastroenterology, Toranomon Hospital, Tokyo, JPN.
Cureus
|February 3, 2026
概括
食道运动障碍 (EMD) 影响近一半的上部肠道症状患者. 缺食症显著增加了EMD的可能性,突出了食道高分辨率计量 (HRM) 诊断的价值.
科学领域:
- 胃肠病学 胃肠病学
- 消化系统疾病 消化系统疾病
- 诊断医学 诊断医学 诊断医学
背景情况:
- 上部胃肠道 (GI) 症状通常会促使人们对食道运动障碍 (EMD) 进行调查.
- 消化管高分辨率计量 (HRM) 对于诊断EMD至关重要,因为消化管胃腺镜检查 (EGD) 没有发现有机异常.
- 在大型患者队列中,日本对症状和EMD之间的相关性存在有限的数据.
研究的目的:
- 用HRM来确定上部胃肠道症状患者的EMD频率.
- 分析特定症状与被诊断的EMD之间的关系.
- 根据芝加哥分类版本3.0 (CC v3.0) 评估HRM发现.
主要方法:
- 对258名患者进行了回顾性分析,他们接受了首次上部肠道症状的HRM,没有EGD检测到的有机异常.
- 2013年7月至2022年5月期间收集的患者数据.
- 根据CC v3.0.0.的EMD患病率和症状相关性的评估.
主要成果:
- 在45.3%的患者中诊断出食道运动障碍 (EMD) (117/258).
- 缺食是最常见的症状 (39.1%),在这些患者中,EMD患病率显著更高 (65.3%,p < 0.001).
- 在患有EMD的失消症患者中,45.5%被诊断出阿哈拉西亚 (I-III类型).
结论:
- 几乎一半的上部肠道症状和EGD正常发现的患者有EMD被HRM诊断出来 (CC v3.0).
- 缺食症是EMD的强有力的指标,包括阿哈拉西亚.
- HRM是诊断EMD患者持续上部肠道症状的有价值的工具,特别是那些有食障碍的患者.
相关概念视频
01:20Gastrointestinal Motility Disorders
1.2K
Gastrointestinal or GI motility disorders are characterized by irregular gastrointestinal tract movements, disrupting food transit from the mouth to the anus. They are caused by damage or dysfunction in gut muscles or nerves. These disorders can cause symptoms such as severe constipation, diarrhea, abdominal pain, and swallowing difficulties. Disorders can affect any segment of the GI tract and range widely in severity, from common conditions like GERD to life-threatening conditions like...
1.2K
01:16Drugs Used in Upper Respiratory Disorders: Overview
661
Upper respiratory tract disorders, including viral infections and allergic rhinitis, cause significant discomfort and disrupt daily life. Managing these conditions involves a variety of drugs, such as antihistamines, intranasal steroids, decongestants, antitussives, expectorants, and mucolytics. Specific examples of drugs in each category are provided.
Antihistamines (e.g., Benadryl) block histamines from binding. Histamines are chemicals released during an allergic reaction in the body. As a...
Antihistamines (e.g., Benadryl) block histamines from binding. Histamines are chemicals released during an allergic reaction in the body. As a...
661
01:26Imaging Studies III: Gastrointestinal Motility Studies and Virtual Colonoscopy
422
This lesson explores three gastrointestinal imaging techniques: radionuclide testing, colonic transit studies, and virtual colonoscopy.
Radionuclide Testing
Radionuclide testing is a sophisticated medical technique for assessing gastrointestinal motility. It focuses on gastric emptying and colonic transit time. Radioactive markers track the movement of food through the digestive system, providing insights into gastrointestinal disorders.
In gastric emptying studies, a meal's liquid and...
Radionuclide Testing
Radionuclide testing is a sophisticated medical technique for assessing gastrointestinal motility. It focuses on gastric emptying and colonic transit time. Radioactive markers track the movement of food through the digestive system, providing insights into gastrointestinal disorders.
In gastric emptying studies, a meal's liquid and...
422
01:30Heart Failure IV: Classification and Diagnostic Evaluation
384
Heart failure can be classified in various ways, with the most common classifications based on physical activity limitations, disease progression, severity, and treatment strategies.The Functional Classification of Heart Failure divides patients into four categories based on physical activity limitation due to symptom burden.Class I: Patients in this class have cardiac disease but no physical activity limitations. Ordinary activities like walking, climbing stairs, or routine tasks do not cause...
384
01:29Disorders of Acid-Base Balance
2.1K
The human body maintains a precise pH range of arterial blood between 7.35 and 7.45. Deviations result in either acidosis (pH < 7.35) or alkalosis (pH > 7.45). These conditions are further classified as respiratory or metabolic disorders based on their underlying cause.
Respiratory Acidosis and Alkalosis
Respiratory acidosis occurs due to an increase in the partial pressure of carbon dioxide PCO2 in the blood. It often arises from shallow breathing or impaired gas exchange caused by...
Respiratory Acidosis and Alkalosis
Respiratory acidosis occurs due to an increase in the partial pressure of carbon dioxide PCO2 in the blood. It often arises from shallow breathing or impaired gas exchange caused by...
2.1K
01:26Anatomy of the Gastrointestinal System
2.8K
The human digestive system is an intricate and essential network for nutrient absorption and waste elimination. It encompasses the gastrointestinal (GI) tract and several accessory organs.
Here's a detailed walkthrough of this complex system:
Here's a detailed walkthrough of this complex system:
2.8K