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Updated: Feb 4, 2026

A Method to Study α-Synuclein Toxicity and Aggregation Using a Humanized Yeast Model
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酵母中基胺通路的破坏会诱导代谢物自我组装成有毒聚合物

Hanaa Adsi1, Myra Gartner1, Claris Simovich1

  • 1Shmunis School of Biomedicine and Cancer Research, The George S. Wise Faculty of Life Sciences, Tel Aviv University, Israel.

The FEBS journal
|February 3, 2026
PubMed
概括

酵母的石基酸途径中的代谢失调会导致有毒的氨酸和氨酸组合,损害细胞活力. 粉样蛋白抑制剂和TMAO治疗挽救了生长,揭示了新陈代谢和粉样蛋白形成之间的联系.

关键词:
代谢过程中的先天性错误.代谢调节 代谢调节代谢物自我组装的代谢物什基马特通道的路径酵母酵母是一种酵母.

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