基线和内在能力的变化与事件心血管疾病的关联:一个多队列研究
Lulu Tang1,2, Changcui Qiu1,2, Xiaoli Yu2
1Tongji University School of Medicine Shanghai China.
Journal of the American Heart Association
|February 3, 2026
概括
内在能力 (IC) 的下降,包括身体和精神能力,与心血管疾病 (CVD) 风险的增加有关. 监控IC可能有助于预防心血管疾病.
科学领域:
- 老年学是一门学科.
- 流行病学 流行病学
- 公共卫生 公共卫生
背景情况:
- 心血管疾病 (CVD) 是全球主要的死亡原因.
- 内在能力 (IC) 是个人的身体和精神能力的综合衡量标准.
- 在IC状态,IC的变化,和事件心血管疾病风险之间的关联需要进一步调查.
研究的目的:
- 检查基线内在容量 (IC) 与患心血管疾病 (CVD) 的风险之间的关系.
- 调查IC随时间的变化如何影响发生心血管疾病的风险.
- 分析这些协会跨越多样化,全国代表的老龄化队伍.
主要方法:
- 利用了来自四个大型国际衰老队伍的数据:查尔斯,HRS,MHAS和SHARE.
- 评估了五个领域的内在能力 (IC):运动,认知,活力,感官和心理.
- 采用Cox的比例危险模型来分析基于IC状态和变化的事件心血管疾病风险.
主要成果:
- 在基线时,在两个或两个以上的IC领域中受损的个体显示出发生性心血管疾病的风险明显更高.
- 与具有强大的IC相比,随着时间的推移表现出稳定的受损IC的参与者心血管疾病风险增加.
- 特定危险比率 (HRs) 表示所有队列中与IC损伤相关的心血管疾病风险增加.
结论:
- 基线内在能力 (IC) 损伤和持续性损伤都与心血管疾病 (CVD) 的风险增加有关.
- 定期评估和监测内在能力 (IC) 可以作为心血管疾病 (CVD) 的预防策略.
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