尼姆 (Azadirachta indica) 种子提取物的依赖溶剂的生物活性成分和抗真菌潜力,可对抗菌毒性Aspergillus物种
Javid Ali1, Muhammad Akram1, Muhammad Zahoor2
1Pakistan Council of Scientific and Industrial Research Laboratories Complex, Peshawar, Khyber Pakhtunkhwa, Pakistan.
Chemistry & biodiversity
|February 3, 2026
概括
尼姆种子提取物显示出强大的抗真菌和抗亚弗拉托基因性质对抗阿斯伯吉路斯物种. 乙醇提取物是最有效的,它显著抑制了真菌生长和亚拉托克辛的产生.
科学领域:
- 农业科学 农业科学
- 菌类学 菌类学是指菌类学.
- 自然产品化学 自然产品化学
背景情况:
- 寄生虫和青虫是重要的农业害虫.
- 这些真菌产生的亚毒素对健康构成严重风险.
- 尼姆 (Azadirachta indica) 是一种具有已知的药用特性的植物.
研究的目的:
- 为了确定尼姆种子提取物 (NSE) 的生物活性成分.
- 为了评估NSE对阿斯伯吉卢斯菌种的抗真菌和抗亚弗拉托基因疗效.
- 评估尼姆种子粉 (NSP) 作为生物防腐剂的潜力.
主要方法:
- 使用各种溶剂 (乙,乙酸乙烯,,甲醇,乙醇) 提取尼姆种子.
- 气色谱-质谱法 (GC-MS) 用于化学分析.
- 抗真菌活性和偏素抑制在体外和料试验中进行了测试.
主要成果:
- 在NSE.中确定了特定于溶剂的生物活性化合物.
- 乙醇提取物显示出最高的抗真菌功效,在31.25mg/ml的剂量下抑制了45%的菌根生长.
- 甲醇和乙醇提取物在250毫克/毫升的剂量下显著抑制了亚毒素的产生 (>90%).
- 在料试验中,尼姆种子粉 (30%度) 完全抑制了青素的产生.
结论:
- 尼姆种子提取物具有显著的抗真菌和抗亚弗拉托基因性质.
- 乙醇和甲醇提取物特别有效地对抗阿斯伯吉勒斯菌种和亚拉托克辛的产生.
- 尼姆种子粉作为天然生物防腐剂在料和食品中表现有前途.
关键词:
亚斯伯吉勒斯 (Aspergillus flavususus) 是一种有的植物.这是一种寄生虫,Aspergillus parasiticus.抑制阿弗拉托克辛的抑制作用气色谱学 质谱学 (GCMS)尼姆种子提取物 尼姆种子提取物更多相关视频
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