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Updated: May 2, 2026

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绘制与阿尔茨海默氏病相关的蛋白质变体,通过基于质谱的新序列测序辅助策略

Daria D Emekeeva1, Jinfeng Chen2, Yang Yang2

  • 1V.L. Talrose Institute for Energy Problems of Chemical Physics, N.N. Semenov Federal Research Center for Chemical Physics, RAS, Moscow, Russia.

Journal of Alzheimer's disease : JAD
|February 3, 2026
PubMed
概括

这项研究开发了一种生物信息学管道,用于在蛋白质组数据中识别阿尔茨海默病 (AD) 特定的氨基酸替代物 (AAS). 这些发现揭示了AD的新型分子特征和潜在生物标志物.

关键词:
阿尔茨海默氏症的疾病是阿尔茨海默氏症.氨基酸替代的氨基酸替代方法质谱测量质谱测量质谱测量质量测量质谱测量质量测量质量测量质量测量质量测量质量测量质量测量质量测量质量测量质量测量质量测量质量测量质量测量质量测量质量测量质量测量质量测量质量测量质量测量质量测量神经退行症的神经退行症的新序列化 de novo 序列化蛋白质形式的蛋白质形式蛋白质组学 蛋白质组学

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