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Updated: Feb 5, 2026

Generation of Human Chimeric Antigen Receptor Regulatory T Cells
10:29

Generation of Human Chimeric Antigen Receptor Regulatory T Cells

Published on: January 3, 2025

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细胞因子工程化学抗原受体-T细胞疗法:如何平衡有效性和毒性

Xinru Zhang1,2,3, Gulizeba Aimaiti1,2,3, Yuanye Guan1,2,3

  • 1Engineering Research Center of Cell & Therapeutic Antibody, Ministry of Education, and School of Pharmacy, Shanghai Jiao Tong University, Shanghai, China.

Advanced science (Weinheim, Baden-Wurttemberg, Germany)
|February 3, 2026
PubMed
概括

卡尔-T细胞疗法对固体瘤有希望,但面临着瘤微环境和细胞因子释放综合征 (CRS) 和神经毒性 (ICANS) 等毒性的挑战. 用细胞因子对CAR-T细胞进行工程设计和管理这些毒性的策略对于改善患者的治疗结果至关重要.

关键词:
汽车汽车工程 工程在CAR-T细胞中.在CRS中,您可以使用CRS.癌症治疗疗法 癌症治疗细胞因子 细胞因子

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