为患有癌症的青少年和年轻成年人开发与健康相关的生活质量工具
Samantha Claire Sodergren1, Olga Husson2,3,4, Silvie Janssen2,4,5
1School of Health Sciences, University of Southampton, Southampton, United Kingdom.
JAMA network open
|February 3, 2026
概括
为患有癌症的青少年和年轻人 (AYA) 开发了一种新的与健康相关的生活质量 (HRQOL) 调查问卷. 该工具评估了与AYA相关的问题,为临床使用提供了可靠的测量方法.
科学领域:
- 在瘤学瘤学.
- 心理测量 心理测量 心理测量
- 青少年和年轻人的健康 (AYA)
背景情况:
- 在青春期和青春期的癌症诊断显著影响发展阶段和与健康有关的生活质量 (HRQOL).
- 现有的HRQOL措施可能无法充分捕捉到这一人口群的独特关注.
- 需要专门的问卷来对癌症患者的AYA进行全面的HRQOL评估.
研究的目的:
- 为患有癌症的青少年和年轻人 (AYAs) 量身定制新的HRQOL问卷.
- 为EORTC QLQ-C30创建一个补充工具,专注于AYA特定问题.
- 为了确保问卷对AYA具有相关性和重要性的HRQOL方面进行测量.
主要方法:
- 一项系统的文献审查和对AYA和医疗保健专业人员 (HCP) 的采访为这项研究提供了信息.
- 从欧洲和亚洲的19个癌症治疗中心招募了参与者.
- 数据分析涉及253名AYA和28名医疗人员的调查答案,使用探索性因子分析和可靠性测试 (Cronbach's α).
主要成果:
- 开发了一个30项,5个子级别的问卷,涵盖活动限制,生活中断,与癌症相关的担忧,自尊,人际关系和积极的变化.
- 可靠性测试显示了良好的内部一致性 (克朗巴赫的α 0.6590.770).
- 发现的关键问题包括区分重要的生活方面 (89%) 和动机 (84%),对一些人来说,外表和生育是优先考虑的问题 (24%).
结论:
- 成功开发和测试了一种对癌症患者的文化敏感和可靠的HRQOL测量工具.
- 该问卷涉及各种癌症类型和治疗的不同AYA人群相关的问题.
- 这种新的HRQOL工具有可能成为AYA瘤学中临床试验和常规实践的有效工具.
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