美国双相情感障碍相关死亡率趋势,1999-2023年:美国疾病预防控制中心 (CDC) 的WONDER数据库分析
Sowmya Kolluru1, Mustafa Beidas2, Olivia Foley2
1Creighton University School of Medicine, Omaha, NE, USA. sowmyakolluru@creighton.edu.
International journal of bipolar disorders
|February 3, 2026
概括
双极性障碍 (BD) 的死亡率有所增加,特别是在老年人,女性和非西班牙裔白人人口中. 在农村地区和中西部地区观察到较高的死亡率,突出显示了BD结果的人口差异.
科学领域:
- 精神病学和流行病学 精神病学和流行病学
- 公共卫生和生物统计学
背景情况:
- 双极性障碍 (BD) 带来了诊断上的挑战和严重的残疾负担.
- 了解BD病因和改善患者的治疗结果需要进一步的研究.
- 对针对性干预来说,鉴别与BD相关的死亡率的人口趋势至关重要.
研究的目的:
- 分析双极性障碍 (BD) 死亡率的人口趋势.
- 为了确定不成比例地受到BD死亡率影响的特定人群.
- 为未来对双极性障碍的管理策略提供信息.
主要方法:
- 利用CDC WONDER数据库获取1999-2023年间的死亡率数据.
- 按种族/种族,性别,年龄,农村/城市指定和人口普查地区分层数据.
- 使用joinpoint分析来评估趋势和统计学意义.
主要成果:
- 在研究期间,与BD相关的死亡率显著增加,特别是随着年龄的增长.
- 女性,非西班牙裔白人队列,农村地区和中西部地区的死亡率更高.
- 在各种人口群体中观察到年龄调整后死亡率的统计显著增加.
结论:
- BD死亡率趋势显示出显著的人口差异,需要集中注意力.
- 这些发现可以指导未来对双极性障碍的管理策略和公共卫生干预措施.
- 建议对心理健康资源利用和早期治疗进行进一步的研究.
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