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对lirafugratinib的复发性耐药性突变在FGFR2驱动的瘤中告知了治疗序列

Francesco Facchinetti1, Antoine Hollebecque2, Rémy Barbé2

  • 1Institut Gustave Roussy Paris France.

Clinical cancer research : an official journal of the American Association for Cancer Research
|February 3, 2026
PubMed
概括

连续使用不可逆转的FGFR抑制剂lirafugratinib和futibatinib可以克服耐药性突变. 这一策略在治疗FGFR2驱动的癌症方面是有前途的,尤其是在初始治疗失败后.

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