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Updated: Feb 5, 2026

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特兰胺酸玻尿酸加滴液矛盾地增加了补体激活:一个PATCH试验二次研究

Nicolle Barmettler1, Elizabeth R Maginot, Ernest E Moore

  • 1From the Division of Acute Care Surgery, Department of Surgery (N.B., E.R.M., F.I.G., C.M.W., T.B.M., A.C., K.S.S., D.H., G.E.V., R.H., C.D.B.), University of Nebraska Medical Center, Omaha, Nebraska; Department of Surgery (E.E.M., J.G.C.), Ernest E Moore Shock Trauma Center, Denver Health; Department of Surgery (H.B.M.), AdventHealth Porter, Denver, Colorado; Department of Cardiology (D.F.D.), Bern Center for Precision Medicine, University Hospital of Bern, Bern, Switzerland; School of Medicine and Psychology (R.G.), Australian National University, Canberra, Australia; Department of Biological Sciences, Hunter College (I.M.B.), New York, New York; The Australian Centre for Blood Diseases (R.L.M.), Monash University; Emergency and Trauma Centre (B.M.), Alfred Health, Melbourne, Australia; Department of Surgery (M.A.S.), Uniformed Services University of Health Sciences, Bethesda, Maryland; Section of Trauma and Acute Care Surgery, Department of Surgery (S.E.R.), University of Chicago Pritzker School of Medicine, Chicago, Illinois; Sauaia Statistical Solutions, L.L.C. (A.S.), Denver, Colorado; and Department of Cellular and Integrative Physiology (C.D.B.), University of Nebraska Medical Center, Omaha, Nebraska.

The journal of trauma and acute care surgery
|February 3, 2026
PubMed
概括

特兰胺酸 (TXA) 在创伤患者中没有减少早期补充激活. 矛盾的是,TXA在24小时后增加了补充激活,这表明它在炎症反应中起着复杂的作用,并质疑最佳剂量策略.

关键词:
特兰克萨姆酸是什么意思补充激活是补充的激活.纤维化解是一种纤维化解.

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