评估沙特瘤学准备的现实世界数据标准化和质量提升的准备
Almaha Alfakhri1, Ohoud Almadani1, Ibrahim Asiri1
1Saudi Food and Drug Authority, Riyadh, Kingdom of Saudi Arabia.
JCO clinical cancer informatics
|February 3, 2026
概括
沙特瘤真实世界数据 (RWD) 与mCODE框架相适度一致,但在数据完整性方面存在重大差距. 观察到高精度,但为了更广泛的研究和监管用途需要标准化.
科学领域:
- 在瘤学瘤学.
- 医疗信息学 医疗信息学
- 数据科学数据科学数据科学
背景情况:
- 现实世界数据 (RWD) 在瘤学研究中至关重要,但数据质量和标准化问题仍然存在.
- 标准化瘤学数据对于可靠的监管决策和临床实践进步至关重要.
研究的目的:
- 评估沙特瘤学RWD对标准化的准备情况.
- 评估来自沙特医疗保健中心的瘤RWD的完整性和准确性.
主要方法:
- 从5个沙特医疗中心提取了超过20,000名成人癌症患者的非身份电子健康记录.
- 评估与最小常见瘤学数据元素 (mCODE) 框架的调整.
- 通过定义的指标评估数据的完整性和准确性.
主要成果:
- 适度的整体对齐 (62.43%) 与mCODE域,患者域显示的最高对齐 (71.43%).
- 数据完整度低至中等 (49.02%),常见癌症和罕见癌症之间存在差异.
- 高整体数据准确性 (95.03%),罕见的癌症显示出更高的准确性.
结论:
- 沙特瘤学RWD表现出良好的准确性,但需要提高标准化的完整性.
- 采用像mCODE这样的标准化数据框架对于提高互操作性至关重要.
- 标准化的RWD是必要的,以支持全国性的瘤学研究和监管应用.
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