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Updated: Feb 5, 2026

An Organotypic High Throughput System for Characterization of Drug Sensitivity of Primary Multiple Myeloma Cells
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蛋白质组子单元PSMD1是多发性骨髓瘤的关键治疗标

Ting Du1, Teng Fang1, Sindhu C Pillai2

  • 1Dana-Farber Cancer Institute, Boston, Massachusetts, United States.

Blood
|February 3, 2026
PubMed
概括

过度表达PSMD1预测多发性骨髓瘤 (MM) 的预后不佳. 通过脂质纳米颗粒 (LNP) 传递的siRNA针对PSMD1,有效地减少了癌症的生长,并在临床前模型中克服了耐药性.

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