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Updated: Feb 5, 2026

Setting a Successful Sorting for Extracellular Vesicle Isolation
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NPM1通过特定RNA动因结合和相分离调解mRNA分类到细胞外囊

Kaixiang Zhang1, Gaoge Sun1, Xiangzheng Liu2

  • 1School of Pharmaceutical Sciences, State Key Laboratory of Membrane Biology, Tsinghua-Peking Center for Life Sciences, Key Laboratory of Bioorganic Phosphorous Chemistry and Chemical Biology (Ministry of Education), Tsinghua University, Beijing, China.

Advanced science (Weinheim, Baden-Wurttemberg, Germany)
|February 3, 2026
PubMed
概括

这项研究揭示了核胺1 (NPM1) 蛋白质将特定的信使RNA (mRNA) 分类为细胞外囊泡 (EV). 在癌症患者的EV中增加的NPM1和EGFRmRNA表明在疾病中起作用.

关键词:
外基因组是外基因组的组成部分.细胞外囊泡中的细胞外囊泡.mRNAs 是一个mRNAs.多个体的多个体的身体.核胺核胺是一种阶段分离的相位分离.

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