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Updated: Feb 5, 2026

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发生在前列腺瘤的微环境:离子通道和超染色体DNA驱动表型可塑性

Sara Darbandi1, Alfonso Urbanucci2,3,4, Sini Hakkola3

  • 1Department of Urology, Icahn School of Medicine at Mount Sinai, New York, USA.

The Prostate
|February 3, 2026
PubMed
概括

离子通道和染色体外DNA (ecDNA) 通过调节可塑性来推动前列腺癌 (PCa) 的进展和治疗耐药性. 针对这些元素提供了新的策略来克服先进PCa的阻力.

关键词:
皮质 - 介质细胞过渡 (EMT)离子通道 离子通道介质细胞-上皮细胞过渡 (MET)转移 转移 转移 转移微观环境是一个微观环境.现象型的风景景观.前列腺癌是前列腺癌.治疗目标化治疗目标化瘤复发 瘤的复发

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