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Updated: Feb 5, 2026

Investigation of Macrophage Polarization Using Bone Marrow Derived Macrophages
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由MIF驱动的纤维细胞衍生CCL2通过巨细胞极化调节促进关节囊纤维化

Yuxin Zhang1, Jiling Ye2, Yuxiang He3

  • 1Department of Rehabilitation Medicine, Hainan Western Central Hospital, Danzhou, Hainan 571700, China; Department of Oral Surgery, Shanghai Ninth People's Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 200011, China; Shanghai Key Laboratory of Orthopedic Implants, Shanghai Ninth People's Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 200011, China.

International immunopharmacology
|February 3, 2026
PubMed
概括

巨细胞迁移抑制因子 (MIF) 在创伤后关节收缩 (PTJC) 中驱动炎症和纤维化,通过增加来自纤维细胞的CC动机化学基因连接体2 (CCL2) 生产. 抑制MIF可以降低CCL2,减轻PTJC的进展.

关键词:
在C-C基因基因基因合体2的基因基因合体.慢性炎症是一种慢性炎症.纤维母细胞细胞是如何形成的纤维化 纤维化 纤维化巨细胞是一个巨细胞.巨细胞迁移抑制因子

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