低剂量CT肺癌查中的辐射剂量的变化:现实世界的多中心协议比较
J Đekić Malbaša1, P Kuzmanović2, B Zarić1
1Faculty of Medicine, University of Novi Sad, Hajduk Veljkova 3, 21000, Novi Sad, Serbia; Institute for Pulmonary Diseases of Vojvodina, Put dr Goldmana 4, 21204, Sremska Kamenica, Serbia.
Radiography (London, England : 1995)
|February 3, 2026
概括
塞尔维亚的低剂量计算机断层扫描 (LDCT) 肺癌查显示中心之间剂量可变性,但仍在国际安全限制内. 建议进行持续的监测和协议协调,以确保一致和安全的查.
科学领域:
- 放射学和医学成像学 医学成像学
- 在瘤学瘤学.
- 公共卫生 公共卫生
背景情况:
- 低剂量计算机断层扫描 (LDCT) 对早期肺癌检测至关重要.
- 在LDCT中的辐射剂量在不同的医疗保健设施之间可能会有很大的差异.
- 评估这种变异性是确保患者安全和查有效性的关键.
研究的目的:
- 评估LDCT肺癌查中的患者辐射剂量变异性在塞尔维亚沃伊沃迪纳的三个中心.
- 评估是否符合国际建议和ALARA (尽可能低的合理实现) 原则.
- 在LDCT检查中确定辐射剂量的预测因子.
主要方法:
- 一组3479名高风险参与者接受了基线LDCT查.
- 收集的数据包括CT剂量指数 (CTDIvol),剂量长度产物 (DLP),管电压 (kVp) 和管电流时间产物 (mAs).
- 多重线性回归被用来确定CTDIvol的预测因素,包括中心,kVp,mAs和患者因素.
主要成果:
- 对所有剂量参数 (p < 0.001) 观察到显著的中心间变异性.
- 平均CTDIvol在0.58-1.63mGy之间,DLP在21.0-65.2mGy cm之间,有效剂量在0.29-0.92mSv之间.
- 查部位和kVp是CTDIvol最强的预测因素,解释了91%的差异;所有剂量都低于2mSv.
结论:
- 塞尔维亚的LDCT查剂量符合国际建议和ALARA原则.
- 站点间剂量变化需要持续监测以优化图像质量并最大限度地减少辐射暴露.
- 系统的剂量跟踪,协议协调和医学物理学家的参与对于安全有效的LDCT肺癌查至关重要.
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