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Updated: Feb 5, 2026

Identification of Mediators of T-cell Receptor Signaling via the Screening of Chemical Inhibitor Libraries
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对一种新的PGAM5特异性抑制剂进行查和鉴定,以减轻多器官损伤的作用

Lin Chen1, Haibo Li2, Qingtain Zhu1

  • 1Pancreatic Center, Department of Gastroenterology, Yangzhou Key Laboratory of Pancreatic Disease, The Affiliated Hospital of Yangzhou University, Yangzhou University, Yangzhou 225000, China.

Journal of advanced research
|February 3, 2026
PubMed
概括

研究人员确定了Plantainoside D (PD) 作为第一个天然的小分子抑制剂,向PGAM5,这是死亡亡的关键调节剂. 在多种器官损伤模型中,PD表现出广泛的保护作用,提供了一个有前途的治疗策略.

关键词:
线粒体中的线粒体.尸体灭 (Necroptosis) 是一种死亡的过程.器官受伤是指器官受伤.这是一个PGAM5PGAM5.植物化物D

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