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对患者报告的功能运动障碍的结果指标的多中心验证
Rosa Michaelis1,2, Leonie Hagedorn3, Anne Weissbach4,5
1Department of Neurology, Knappschaft Kliniken University Hospital Bochum, Ruhr University Bochum, Bochum, Germany rosa.michaelis@knappschaft-kliniken.de.
Journal of neurology, neurosurgery, and psychiatry
|February 3, 2026
概括
功能运动障碍问卷 (FMDQ) 是一个经过验证的患者报告的结果指标,对于在临床护理和研究中评估功能运动障碍 (FMDs) 至关重要.
科学领域:
- 神经学 神经学
- 临床心理学 临床心理学
- 康复医学 康复医学 康复医学
背景情况:
- 功能性运动障碍 (FMDs) 缺乏经过验证的患者报告结果指标 (PROM),阻碍了临床护理和研究.
- 这种差距需要开发和验证一个可靠的工具来评估患者的体验.
研究的目的:
- 通过多中心前性研究验证功能运动障碍问卷 (FMDQ).
- 确定FMDQ的心理测量特性,用于临床实践和研究.
主要方法:
- 确认因素分析 (CFA) 评估了FMDQ的四个因素结构 (运动症状,日常活动障碍,非运动症状,社会功能).
- 评估了内部一致性,地板/天花板效应以及标准/构造有效性 (使用SF-36,PHQ-15,FAS,FMDQ-CR).
- 使用基于分布和基于的方法确定最小临床重要差异 (MCID).
主要成果:
- 对于FMDQ,CFA支持了一个四因素模型.
- 调查问卷显示了适当的内部一致性,缺乏地板/天花板效应.
- 显著的相关性证实了标准和构造的有效性;MCID估计在8-20点之间.
结论:
- 功能性运动障碍问卷 (FMDQ) 是一种心理测量上健全的PROM.
- FMDQ适用于功能运动障碍的临床实践和治疗试验.
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