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Updated: Feb 5, 2026

Establishment of a Surgically-induced Model in Mice to Investigate the Protective Role of Progranulin in Osteoarthritis
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删除LOXL2会引发关节骨关节炎,而过度表达会保护它免受NF-κB诱导的冠状细胞亡

Rajnikant Dilip Raut1, Chumki Choudhury1, Faiza Ali1

  • 1Translational Dental Medicine, Boston University Henry M. Goldman School of Dental Medicine, Boston, MA, USA.

International journal of oral science
|February 3, 2026
PubMed
概括

酸氧化酶-Like-2 (LOXL2) 缺乏会通过增加炎症和软骨破坏,使关节骨关节炎 (TMJ-OA) 恶化. 然而,LOXL2治疗可以防止这些TMJ-OA效应.

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