工程细菌疗法通过代谢竞争和毒性沉默来抑制输血性大肠杆菌

Guozhen Ma1,2,3,4, Ruiying Liu4, Xueping Li5

  • 1National Key Laboratory of Intelligent Tracking and Forecasting for infectious Diseases, Beijing Ditan Hospital, Capital Medical University, Beijing, China.

Nature communications
|February 3, 2026
PubMed
概括

一种新的双机制疗法,使用工程细菌和糖化合物,在微球中输送,有效治疗输血性大肠杆菌 (EHEC) 感染. 这种方法可以减少病原体的殖民和毒性,而不会释放有害的毒素,为抗生素提供一种安全的替代品.

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