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Updated: Feb 5, 2026

The Use of Reverse Phase Protein Arrays RPPA to Explore Protein Expression Variation within Individual Renal Cell Cancers
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蛋白质C端变异会影响蛋白质静止

Ching-Yu Chu1,2, Shu-Yu Hsu1,2, Chi-Wei Yeh1

  • 1Institute of Molecular Biology, Academia Sinica, Taipei, Taiwan.

Nature communications
|February 3, 2026
PubMed
概括

改变的蛋白C-终端可以令人惊地稳定或破坏蛋白质的稳定性,影响蛋白质组的多样性. 这项研究揭示了与疾病相关的C端变化会影响蛋白质稳定性,超出质量控制范围.

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