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区分与超重/肥胖相关的食物和货币奖励提示处理异常:一个ALE元分析
Na Wang1, Mingyue Xiao1, Xiaofang Hou2
1Key Laboratory of Cognition and Personality, Faculty of Psychology, Ministry of Education, Southwest University, Chongqing, PR China.
International journal of obesity (2005)
|February 3, 2026
概括
超重/肥胖 (OW/OB) 个体在处理食物与金钱奖励时表现出不同的大脑活动模式. 这些神经认知差异突出显示了奖励敏感性和决策能力的改变,这表明针对肥胖的有针对性的干预措施.
科学领域:
- 神经科学是一个神经科学.
- 精神病学是一个精神病学.
- 放射学 放射学是一门学科.
背景情况:
- 肥胖是一个全球性的健康问题,在奖励处理中缺乏理解的神经认知差异.
- 了解这些区别对于开发有效的干预措施至关重要.
研究的目的:
- 分析功能性MRI研究,比较超重/肥胖 (OW/OB) 个体对食物和金钱奖励的神经反应与正常体重 (NW) 对照.
- 确定与OW/OB中奖励处理相关的常见和明显的脑异常.
主要方法:
- 在Web of Science,PubMed和PsycInfo的系统文献搜索.
- 激活概率估计 (ALE) 对26项研究 (1065名参与者) 的元分析.
- 使用MRIcroGL与MNI坐标可视化的结果.
主要成果:
- 对于两种奖励类型,左后带带皮层 (PCC) 和胰岛的重叠减少了激活.
- 观察到明显的模式:在食物奖励中,左中额头 (MFG) 的激活减少,在OW/OB中增加了货币奖励.
- 在食物奖励方面,OW/OB显示出尾状体,海马体,ACC和mPFC的激活增加;在金钱奖励方面,下丘脑的激活增加.
结论:
- 在加工食物和金钱奖励方面,OW/OB表现出重叠和明显的神经变化.
- 研究结果表明,在OW/OB中,奖励灵敏度,决策能力和抑制性控制发生变化.
- 针对这些神经机制的奖励类型的具体干预措施对于肥胖管理是必要的.
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