一个三臂,并行组,集群随机对照试验,以评估数字和复杂的生活方式干预措施与2型糖尿病预防的常规护理相比:大庆糖尿病预防研究II (Daqing DPS-II) 的协议
Juan Zhang1,2, Di Li3,2, Yachen Wang1,2
1School of Population Medicine and Public Health, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing, China.
Trials
|February 3, 2026
概括
这项研究评估了数字化和复杂的生活方式干预措施,以预防高风险成年人2型糖尿病 (T2DM). 结果将为T2DM预防计划的现实世界战略提供信息.
科学领域:
- 公共卫生 公共卫生
- 预防医学 预防医学
- 临床试验 临床试验
背景情况:
- 大庆糖尿病预防研究II (Daqing DPS-II) 旨在开发预防2型糖尿病 (T2DM) 的现实世界策略.
- 它建立在最初的"大庆糖尿病预防研究"的成功之上.
- 这项研究重点关注2型糖尿病风险增加的成年人.
研究的目的:
- 评估数字化和复杂的生活方式干预措施在减少T2DM发病率方面的有效性.
- 为了在36个月的时间内将这些干预措施与通常的护理进行比较.
- 评估糖尿病预防的现实世界实施策略.
主要方法:
- 一个三臂,集群随机控制试验,涉及8家工厂的57个集群.
- 患有T2DM风险增加的参与者 (25-55岁) 被随机分配到数字干预,复杂的生活方式干预或常规护理.
- 主要结局包括3年累计T2DM发病率,通过葡萄糖耐受性测试,临床测量和行为数据进行评估.
主要成果:
- 该研究正在进行中;关于T2DM发病率的初步结果正在等待.
- 过程措施将使用RE-AIM框架评估覆盖范围,采用,实施和维护.
- 可行性,可接受性和适当性将通过实施成果框架进行评估.
结论:
- 该研究将提供关于实施人口级数字化和复杂生活方式干预措施以预防糖尿病的证据.
- 成功的策略可以整合到中国和全球的工作场所健康计划中.
- 这项研究旨在预防T2DM和其他非传染性疾病.
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