快速现场评估的诊断价值在内支膜超声导向支膜支膜检查外周肺部病变:一个元分析
Ke-Yu Hsiao1, Hsiu-Ling Lin2, Cheng-Chieh Chen3
1Department of Pathology and Laboratory Medicine, Shin Kong Wu Ho-Su Memorial Hospital, Taipei, Taiwan.
快速现场评估 (ROSE) 显示在内支气管超声波引导的横支气管针吸收 (EBUS-TBNA) 期间诊断外周肺病变 (PPLs) 的高准确性. 这种技术对于高风险患者的肺癌检测是有效的.
科学领域:
- 肺部病理学 肺部病理学
- 在瘤学瘤学.
- 诊断成像 诊断成像 诊断成像
背景情况:
- 低剂量计算机断层扫描 (LDCT) 查可以降低肺癌死亡率.
- 内支支气管超声波导向的跨支气管针吸收 (EBUS-TBNA) 是诊断周围肺病变 (PPL) 的标准.
- 快速现场评估 (ROSE) 提高了EBUS-TBNA的诊断产量,但其对PPL的有效性需要澄清.
研究的目的:
- 在EBUS支气管镜检查期间评估PPL的ROSE诊断准确度.
- 为了确定ROSE在识别PPL中的敏感性和特异性.
- 评估ROSE在支气管镜检查期间肺癌诊断中的作用.
主要方法:
- 在EBUS-TBNA期间对评估PPL的ROSE诊断准确度的研究进行了元分析.
- 搜索包括了PubMed,Embase和Cochrane图书馆的数据库.
- 来自13项研究的数据 (1841个PPL) 用双变的随机效应模型分析,以估计聚合的灵敏度和特异性.
主要成果:
- 分析报告了PPL诊断中ROSE的聚合灵敏度为88.1%和特异性为91.7%.
- 对接受CT的患者的亚组分析显示了更高的准确性:聚合灵敏度为94.2%,特异性为96.9%.
- 通过EBUS使用引导进行采样的ROSE显示了88.5%的聚合灵敏度.
结论:
- 在EBUS支气管镜检查期间,ROSE是一种敏感和特定的技术,用于在PPL中检测肺癌.
- 在接受CT扫描的患者中,ROSE的诊断准确度可能会提高.
- 罗斯提高了EBUS-TBNA对外围肺病变的诊断能力.
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