舌癌的发病率,危险因素和时间趋势:基于人口的研究
Junjie Huang1,2, Wing Sze Pang1, Claire Chenwen Zhong1
1The Jockey Club School of Public Health and Primary Care, Faculty of Medicine, Chinese University of Hong Kong, Hong Kong SAR, China.
Cancer medicine
|February 4, 2026
概括
在全球范围内,舌头癌的发病率各不相同,中南亚承担了最高的负担. 吸烟和酒精等生活方式因素导致男性患病率更高,强调需要进行干预.
科学领域:
- 在瘤学瘤学.
- 流行病学 流行病学
- 公共卫生 公共卫生
背景情况:
- 舌头癌症是全世界最常见的口腔内恶性瘤.
- 了解其全球负担,风险因素和发病率趋势对于公共卫生战略至关重要.
研究的目的:
- 调查舌癌的全球负担和流行病学趋势.
- 为了确定与舌头癌症发病率相关的关键风险因素.
- 分析舌头癌症发病率的人口和地理差异.
主要方法:
- 利用了全球癌症观测中心的数据,五大洲的癌症发病率以及全球疾病负担.
- 采用线性回归来分析发生率和风险因素之间的关联.
- 使用 95% 置信区间的年平均百分比变化 (AAPC) 评估时间趋势.
主要成果:
- 在全球确定了151,338例舌癌病例,年龄标准化率 (ASR) 为1.7/100,000.
- 最高的ASR发生在中南亚 (3.4),北美 (2.3) 和北欧 (2.1).
- 发病率与吸烟,酒精消费和饮食因素有显著的相关性;男性的ASR (2.6) 比女性 (0.86) 高.
结论:
- 在舌头癌症负担上存在显著的地理差异,特别是在中南亚最严重.
- 较高的男性发病率与吸烟和饮酒有关,这强调了改变生活方式的重要性.
- 全球发病率呈上升趋势,像菲律宾这样的例外很少.
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