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带有超薄导管的双校正机器人支气管系统用于诊断具有挑战性的外围肺结节:一个多中心前性试验

Zhending You^1,2, Junfeng Huang^1,2, Feng Wang³

¹Guangzhou Institute of Respiratory Health, State Key Laboratory of Respiratory Disease, National Clinical Research Center for Respiratory Disease, National Center for Respiratory Medicine, The First Affiliated Hospital of Guangzhou Medical University, Guangzhou, Guangdong, China.

|February 4, 2026

概括

使用超薄导管的机器人支气管检查显示了高的诊断收益率 (84.2%) 在没有辐射的情况下挑战外围肺结节 (C-PPNs). 这种新的系统实现了100%的导航成功和最小的并发症,改善了对小或难以到达的肺结节的诊断.

科学领域:

肺部病理学肺部病理学
医疗技术医疗技术医学技术
诊断成像诊断成像诊断成像

背景情况:

传统的支气管检查对具有挑战性的外围肺结节 (C-PPNs) 的诊断产量有限,特别是那些小 (≤20毫米),膜接触或反向角度的肺结节.
使用超薄导管的机器人支气管镜系统 (RBS) 为诊断C-PPNs提供了潜在的进步.

研究的目的:

评估一种具有超薄导管的新型机器人支气管镜系统 (RBS) 的诊断产量和安全性,用于挑战外围肺结节 (C-PPNs).
评估RBS在无辐射条件下的性能,以诊断C-PPNs.

主要方法:

一项前性多中心研究在2022年至2024年期间招募了89名患有C-PPN的患者.
患者接受了机器人支气管镜系统 (RBS) 活检. 诊断产量是基于结节特征进行分析的,后勤回归用于识别诊断成功的预测因素.
结节的特征包括大小 (≤20毫米),膜接触和反向角度 (≤90°).

主要成果:

新型RBS在C-PPN中实现了100%的导航和采样成功.
总的诊断收益率为84.2%,对恶性瘤的敏感度为88.3%.
胸膜接触 (90.6%) 和反角 (89.5%) 的结节产量高于较小的结节 (≤20毫米,75.0%). 肺胸部没有发生,出血是最小的.

结论:

具有超薄导管的新型机器人支气管镜系统 (RBS) 在诊断具有挑战性的外围肺结节 (C-PPNs) 方面表现出卓越的性能.
该系统在没有辐射的情况下实现了高诊断收益率 (84.2%) 和导航成功 (100%),具有有利的安全概况 (0肺胸部).
这项研究为使用先进的支气管镜技术诊断C-PPN建立了有价值的参考.

关键词:

具有挑战性的周围肺结节.机器人支气管镜系统机器人支气管镜系统超薄导管是一种超薄导管.

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