中国人类腺病毒感染的流行病学特征,2020-2023年
Chongyang Li1, Yitong Lin1, Naiying Mao1
1National Key Laboratory of Intelligent Tracking and Forecasting for Infectious Diseases, National Institute for Viral Disease Control and Prevention, Chinese Center for Disease Control and Prevention, Beijing 102206, China.
Biosafety and health
|February 4, 2026
概括
在2020-2023年期间,中国的人类腺病毒 (HAdV) 感染的检测率各不相同,南方的流行率更高,对幼儿的影响更大. 建议进行持续的监测,以跟踪HAdV流行病学.
科学领域:
- 病毒学 病毒学
- 流行病学 流行病学
- 公共卫生 公共卫生
背景情况:
- 在全球范围内,COVID-19大流行改变了呼吸道病毒循环模式.
- 了解人类腺病毒 (HAdV) 流行病学对于公共卫生战略至关重要.
- 在COVID-19后,中国对HAdV感染的数据有限.
研究的目的:
- 调查2020年至2023年中国HAdV感染的流行病学特征.
- 分析检测率,地理分布,季节性,人口统计和HAdV的共感染情况.
- 为HAdV.提供未来监督和控制措施的信息.
主要方法:
- 分析了来自14个哨戒省的急性呼吸道感染 (ARI) 患者的17562个呼吸道样本.
- 使用商业核酸套件检测八种常见的呼吸道病毒,包括HAdV.
- 根据流行病学参数对HAdV阳性病例的统计分析.
主要成果:
- 总体HAdV检测率为5.09%,在2022年下降,并在2023年反弹.
- 与中国北部 (4.76%) 相比,在中国南部 (6.15%) 发现率明显更高.
- 0-2岁的婴儿是受影响最严重的群体 (41.39%),患者中位数年龄为3岁. 同时感染发生在36.01%的病例中,最常见的是人类犀利病毒和呼吸道同胞病毒.
结论:
- 中国的HAdV感染呈现出显著的区域和时间差异.
- 在此期间,中国南部似乎是HAdV流行的主要驱动因素.
- 持续的流行病学监测对于了解HAdV动态和为公共卫生干预提供信息至关重要.
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