辅助的GM-CSF治疗增强了免疫抑制小鼠对系统性Candida auris感染的宿主防御能力

Eliciane Cevolani Mattos1, Kaustav Das Gupta1, Derek Quintanilla1

  • 1Division of Infectious Disease, The Lundquist Institute for Biomedical Innovation at Harbor-University of California, Los Angeles Medical Center, Torrance, CA, United States.

Frontiers in immunology
|February 4, 2026
PubMed
概括

颗粒细胞-巨细胞殖民地刺激因子 (GM-CSF) 免疫疗法改善了多药耐药Candida auris感染的小鼠的生存率和减少了真菌负担. 转基因-CSF显示出作为对这种严重的真菌病原体的辅助疗法的承诺.

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