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Updated: Feb 5, 2026

Pre-clinical Evaluation of Tyrosine Kinase Inhibitors for Treatment of Acute Leukemia
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丢失的ROR2 氨酸激酶受体是通过不适当的整体蛋白β1激活PAH中内皮功能障碍相关的

Ankita Mitra1, Stuti Agarwal1, Ananya Chakraborty1

  • 1Division of Pulmonary and Critical Care (A.M., S.A., A.C., A.R., A.B., A.P., N.A., P.C., A.J., J.A.M.M., E.S.G., V.A.d.J.P.), Stanford University, Palo Alto, CA.

Hypertension (Dallas, Tex. : 1979)
|February 4, 2026
PubMed
概括

受体氨酸激酶类孤儿受体2 (ROR2) 的丧失,通过损害内皮屏障完整性,使肺动脉高血压恶化. 恢复ROR2功能可能为PAH提供新的治疗策略.

关键词:
细胞极性是细胞的极性.内皮细胞是内皮细胞.焦点粘附的焦点粘附.肺动脉高血压 肺动脉高血压血管改造 血管改造 血管改造

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