治疗癌症绝症患者 Delirium 症状的干预措施:一个范围审查
Mari Takeuchi1, Takafumi Miyoshi2, Jun Kako3
1Palliative Care Center, Keio University School of Medicine, Tokyo, Japan.
Journal of palliative medicine
|February 4, 2026
概括
管理癌症患者的痴呆症至关重要,但缺乏足够的证据. 本次审查强调了对干预措施的有限研究,强调需要更多的研究来改善对这一群体的护理.
科学领域:
- 抚慰性护理是一种缓解性护理.
- 在瘤学瘤学.
- 基于证据的医学基于证据的医学.
背景情况:
- 痴呆症是癌症终末期患者常见和令人痛苦的并发症.
- 它显著损害了沟通,决策和生活质量.
- 由于证据不足,目前的指导方针提供了有限的建议.
研究的目的:
- 系统地绘制对癌症终极病人痴呆症症状管理干预措施的文献.
- 确定现有证据库中的空白.
主要方法:
- 根据既定的指导方针进行全面的范围审查 (Arksey和O'Malley,PRISMA-ScR).
- 在多个数据库 (PubMed,Cochrane,Ichushi-Web) 进行了广泛的文献搜索,并进行了最新的搜索.
- 包括研究评估治疗晚期癌症 (预期寿命≤1个月) 的成年人妄的干预措施.
主要成果:
- 七项研究在1640个已识别的文章中符合纳入标准.
- 包括的研究包括四项关于药理干预的RCT,一项关于水分的RCT和两项关于转换阿片类药物的观察性研究.
- 所有研究都集中在绝症癌症患者身上,并评估了妄想症状缓解的结果.
结论:
- 在绝症癌症患者中对妄症状管理的文献有限且异质.
- 进一步的研究对于加强证据基础至关重要.
- 调查结果强调,需要为这种脆弱人群改进临床实践指南.
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