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Updated: Feb 6, 2026

Preparation and Use of HIV-1 Infected Primary CD4+ T-Cells as Target Cells in Natural Killer Cell Cytotoxic Assays
12:07

Preparation and Use of HIV-1 Infected Primary CD4+ T-Cells as Target Cells in Natural Killer Cell Cytotoxic Assays

Published on: March 14, 2011

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在初级CD4+T细胞中,HIV-1 Vpr诱导了一种NFAT控制的转录程序

Johanna Leyens1, Carlos Alberto Vanegas-Torres1, Anthea Darius1

  • 1Institute for Medical Virology and Epidemiology of Viral Diseases, University Hospital Tübingen, Tübingen, Germany.

mBio
|February 4, 2026
PubMed
概括

艾滋病毒-1 Vpr 蛋白显著改变 CD4+ T 细胞的转录组,NFAT 控制了这些变化的近一半. 这种重编程支持HIV-1复制,并影响T细胞激活和细胞循环.

关键词:
CD4+ T 细胞是 CD4+ T 细胞.G2 逮捕 逮捕 逮捕艾滋病病毒-1 艾滋病病毒-1在 NFAT NFAT 中.这就是Vpr Vpr.细胞循环中的细胞循环.转录网络是一种转录网络.

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