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Updated: Feb 6, 2026

High-throughput Antiviral Assays to Screen for Inhibitors of Zika Virus Replication
10:16

High-throughput Antiviral Assays to Screen for Inhibitors of Zika Virus Replication

Published on: October 30, 2021

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通过多阶段的虚拟查和实验验证实,通过可解释机器学习驱动的新型DENV NS2B-NS3蛋白酶抑制剂的识别

Shengjie Hu1,2, Yan Xiao1,2, Hailun Jiang3

  • 1Key Laboratory of Structure-Based Drug Design & Discovery of Ministry of Education, and Key Laboratory of Intelligent Drug Design and New Drug Discovery of Liaoning Province, Shenyang Pharmaceutical University, Shenyang, 110016, China.

Molecular diversity
|February 4, 2026
PubMed
概括

研究人员开发了机器学习模型,以寻找新的登革热药物. 他们通过预测登革热病毒NS2B-NS3蛋白酶的抑制,将化合物5确定为一个有前途的候选物.

关键词:
登革热是一种登革热.机器学习是机器学习.在NS2B-NS3蛋白酶中.这就是 SHAP SHAP 的意思.虚拟选是一个虚拟的选.

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