在泰国,在杀过程中在狗和猫身上发现了致病性LeptoSpira物种
Metawee Thongdee1, Somjit Chaiwattanarungruengpaisan1, Weena Paungpin1
1The Monitoring and Surveillance Center for Zoonotic Diseases in Wildlife and Exotic Animals, Faculty of Veterinary Science, Mahidol University, Salaya, Nakhon Pathom Province, Thailand.
PLoS neglected tropical diseases
|February 4, 2026
概括
在泰国,9.9%的狗和猫身上检测到LeptoSpira细菌,包括可以感染人类的致病物种. 这凸显了从伴侣动物传播白病的风险以及需要采取控制措施的必要性.
科学领域:
- 兽医医学 兽医医学 兽医医学
- 动物传播疾病 动物传播疾病
- 分子流行病学分子流行病学
背景情况:
- 牛螺杆菌引起的动物性疾病牛螺杆菌病在全球范围内被诊断不足.
- 在动物库中无症状携带,包括狗和猫等伴侣动物,使传播控制复杂化.
- 在泰国伴侣动物中缺乏关于Leptospira的分子数据.
研究的目的:
- 调查泰国狗和猫的LeptoSpira感染的流行率和分子流行病学.
- 为了确定在伴侣动物中循环的特定致病性Leptospira物种.
- 评估从这些动物传播人体白病的潜在风险.
主要方法:
- 在泰国七个省份收集了567只接受绝育的狗和猫的尿液样本.
- 使用PCR准rrs基因进行了勒普托斯皮拉DNA的选.
- 阳性样本经过桑格测序,用于物种识别.
主要成果:
- 在9.9% (56/567) 的动物 (11.2%的狗,8.3%的猫) 中检测到Leptospira DNA.
- 识别的物种包括L. interrogans,L. weilii和L. borgpetersenii. 这些物种都被发现了.
- 该研究报告了泰国伴侣动物中首次分子检测L. yasudae.
结论:
- 泰国的临床健康的狗和猫拥有已知的致病性LeptoSpira物种,可引起人类的LeptoSpirosis.
- 伴侣动物在被调查地区每天都会对人类白病的传播构成潜在的风险.
- 加强监测,物疫苗接种计划和公众宣传活动对于减轻人类感染风险至关重要.
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