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Updated: Feb 6, 2026

Identification of EGFR and RAS Inhibitors using Caenorhabditis elegans
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Identification of EGFR and RAS Inhibitors using Caenorhabditis elegans

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新的抗增殖性皮拉/奎诺林混合物:作为EGFR抑制剂的设计,合成和生物评估

Mai E Shoman1, Heba A Hassan1,2, Hesham A M Gomaa3

  • 1Medicinal Chemistry Department, Faculty of Pharmacy, Minia University, Minya, Egypt.

Chemical biology & drug design
|February 4, 2026
PubMed
概括

新的pyrazole/quinoline混合物显示出对人类癌细胞具有显著的抗增殖作用. 混合11i特别抑制EGFR,显示出作为一种新型癌症治疗剂的潜力.

关键词:
欧洲农业基金会 (EGFR) 是一个基金.这是一种反扩散药物.氨酸是什么 氨酸是什么皮拉 (pyrazole) 是一种可怕的药物.昆氨酸 (quinoline) 是一种氨酸.

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