对于认知障碍的结合性跨电刺激 (tES) 和认知训练 (CT):临床应用和基础研究的证据
Shu Xing1, Yuan Yuan1, Ping Ren2
1Medical School, Kunming University of Science & Technology, Kunming, Yunnan 650500, China.
Behavioural brain research
|February 4, 2026
概括
将跨电刺激 (tES) 与认知训练 (CT) 结合起来,有望在各种神经和精神疾病中改善认知功能. 需要进一步的研究来优化参数,并探索动物模型中的机制.
科学领域:
- 神经科学是一个神经科学.
- 神经学 神经学
- 认知科学 认知科学
背景情况:
- 认知障碍是神经精神疾病的一个重大挑战.
- 结合跨电刺激 (tES) 和认知训练 (CT) 提供了一个潜在的治疗途径.
研究的目的:
- 通过患者和动物模型,审查神经系统疾病中结合tES和CT的研究.
- 突出底层的神经机制和潜在的协同效应.
主要方法:
- 对阿尔茨海默病,帕金森病,中风,TBI,精神分裂症,多动症和抑郁症等疾病患者的临床研究的审查.
- 在动物认知障碍模型中分析了单独的tES和CT研究.
主要成果:
- 结合tES和CT可以改善不同患者群体的认知领域 (注意力,记忆力,执行功能).
- 单独的tES和CT在动物模型中显示了空间学习和记忆的好处.
- 综合方法调节大脑网络连接,微循环和神经传递.
结论:
- 结合tES和CT,在多种神经疾病中证明了对认知缺陷的治疗潜力.
- tES和CT之间的协同效应需要进一步研究.
- 优化参数和加强动物研究对于未来的临床转化至关重要.
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