在盆腔CT和MRI扫描中对应的解剖标志位置的观察者间变异性
Georgios Andreadis1, Wendy Visser-Groot1, Stephanie M de Boer1
1Dept. of Radiation Oncology, Leiden University Medical Center, P.O. Box 9600, Leiden, 2300 RC, Zuid-Holland, The Netherlands.
概括
在盆腔扫描上放置解剖学标志的观察者间的变异性很高,经常超过声音尺寸. 这挑战了目前使用地标验证可变形图像注册 (DIR) 质量的指导方针.
科学领域:
- 医学成像医学成像
- 辐射疗法 辐射疗法
- 图像分析 图像分析
背景情况:
- 解剖学地标对于验证可变形图像登记 (DIR) 质量至关重要.
- 手动地标的放置取决于观察者的变化.
- 这项研究量化了盆腔扫描中的观察者间变异性.
研究的目的:
- 分析骨盆CT和MRI扫描上解剖学里程碑位置的观察者间变异性.
- 为依赖地标的DIR验证研究提供背景.
- 评估地标位置的变化对质量评估指南的影响.
主要方法:
- 17名观察员对9名宫癌患者的盆腔CT和MRI扫描记录了23个里程碑.
- 使用了三个注释设置:CT-CT,MRI-CT和MRI-MRI.
- 几何中位数量化观察者之间的变化.
主要成果:
- 软组织基准位置的变化范围从2.6毫米到5.6毫米 (Euclidean 距离的中位数).
- 骨解剖学的变化明显较低.
- 可变性与变形大小正相关.
结论:
- 在骨盆地标位置上存在显著的观察者间变异性.
- 这种变化往往超过voxel大小.
- 目前基于里程碑的DIR质量评估指南可能受到质疑.
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