窄带成像对状伤失误率的影响:一个多中心随机并列结肠镜试验
Jiahui Wei1, Song Zhang1, Qiwen Fang1
1Department of Gastroenterology, National Clinical Research Center for Digestive Diseases, Changhai Hospital; National Key Laboratory of Immunity and Inflammation, Naval Medical University, Shanghai, 200433, China.
概括
窄带成像 (NBI) 显著降低了状状病变 (SSL) 的错误率,这是结直肠癌的前体. 这种先进的成像技术与传统的白光成像 (WLI) 相比,提高了检测能力.
科学领域:
- 胃肠病学 胃肠病学
- 内镜检查是指内镜检查.
- 结肠直肠癌查 结肠直肠癌查
背景情况:
- 状状病变 (SSL) 是结肠镜检查后结肠直肠癌的前体.
- 由于微妙的形态学,SSL经常被忽视.
- 狭带成像 (NBI) 对SSL检测的有效性尚不清楚.
研究的目的:
- 为了确定NBI是否可以降低SSL失败率 (SSLMR).
- 为了比较NBI与用于SSL检测的白光成像 (WLI).
主要方法:
- 在CRC查人群中进行多中心,随机合并试验.
- 被随机分配到NBI-first或WLI-first结肠镜的参与者.
- 主要结局:SSLMR;次要结局:近端形多和腺瘤错过率.
主要成果:
- 与WLI相比,NBI显著降低了SSLMR (17.5%与43.6%,P = 0.003).与WLI相比,NBI显著降低了SSLMR (17.5%与43.6%,P = 0.003).
- 此外,NBI还降低了近端状病变和腺瘤的错误率.
- NBI是SSLMR降低 (OR,0.24) 和加强密集监测建议的独立因素.
结论:
- NBI显著降低了SSL,近端状病变和腺瘤的错误率.
- NBI改善了癌前结肠直肠病变的检测.
- 国家结直肠研究所加强了用于预防结直肠癌的监测策略.
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