富含氨酸/氨酸的蛋白质和U2AF1相互作用的酸化依赖调节在早期的结合体组件组件中

Zihan Zhang1, Puspa Kunwar1, Yanbao Yu2

  • 1Department of Chemistry, University of Alabama at Birmingham, Birmingham, AL, 35294, USA.

概括

酸化通过控制氨酸/氨酸丰富 (SR) 蛋白和U2AF1.1之间的相互作用来调节结合体组合. 这项研究揭示了一种通过酸化依赖结合来调节早期结合体形成的保存机制.

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