孕妇中孕妇和胎儿的结局 孕妇中孕妇中孕妇的结局 孕期is pemphigoid
Eve Michaud1, Ethan Bendayan1, Andrea R Spence2
1Faculty of Medicine, McGill University, Montreal, Quebec, Canada.
概括
怀孕期间的皮虫妊娠 (PG) 与孕期糖尿病和产后出血等母亲不良结果的风险增加有关. 然而,在患有这种罕见自身免疫性疾病的母亲的新生儿中没有观察到任何显著的不良影响.
科学领域:
- 产科和妇科 产科和妇科
- 皮肤病学 皮肤病学
- 自免疫性疾病 自免疫性疾病
背景情况:
- 孕期皮炎 (PG) 是一种罕见的自身免疫性孕期水泡性疾病.
- 它通常在第二或第三个三个月表现为的疹斑块和水泡.
- 了解PG对母亲和新生儿健康的影响对于临床管理至关重要.
研究的目的:
- 调查皮虫妊娠症 (PG) 与母亲和新生儿不良结果之间的关联.
- 为了提供关于这个研究不足的疾病的基于人口的数据.
主要方法:
- 使用美国医疗保健成本和利用项目-全国性住院患者样本 (2016-2021) 的回顾性队列研究.
- 与那些没有PG的孕妇相比,孕妇患有PG (ICD-10 O26.4).
- 使用多变量逻辑回归,根据母亲的特征进行调整.
主要成果:
- 在每10万分娩中,PG的发病率为8.6.
- 在非裔美国人,低收入群体和患有甲状腺疾病,吸烟史或病态肥胖的人群中,PG更为普遍.
- PG显著增加了妊娠糖尿病,妊娠高血压,子膜早产早破,剖腹产,产后出血,输血,DIC和败血症的几率.
- 没有与PG相关的显著不良新生儿结局.
结论:
- 怀孕期间的皮虫妊娠症与更高的不良产科结果的可能性有关.
- 这些发现为患者和管理PG的医疗保健提供者提供了有价值的基于人口的见解.
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