在瑞典极度早产12年后的神经发育结果
Fredrik Serenius1, Thomas Abrahamsson2,3, Ulrika Ådén3,4,2
1Department of Women's and Children's Health, Uppsala University, Uppsala, Sweden.
Pediatrics
|February 4, 2026
概括
极度早产 (EPT) 的儿童面临着重大挑战,包括神经发育障碍 (NDD),自闭症谱系障碍 (ASD) 和注意力缺陷多动性障碍 (ADHD) 的更高率在12岁时. 多病症和行为问题也很常见,需要持续的多学科护理.
科学领域:
- 儿科 儿科 儿科
- 神经科学是一个神经科学.
- 发展心理学 发展心理学
背景情况:
- 极度早产 (EPT) 出生 (怀孕27周以下) 与增加神经发育不良结果的风险有关.
- 早期识别和干预对于改善EPT幸存者的长期结果至关重要.
研究的目的:
- 评估神经发育障碍 (NDD),注意力缺陷多动症障碍 (ADHD),自闭症谱系障碍 (ASD),发育协调障碍 (DCD) 和早期青春期EPT儿童全国队列中的行为问题的患病率.
- 了解这些儿童多病症的程度.
主要方法:
- 在瑞典 (2004-2007) 出生的EPT婴儿的国家队列被跟踪到12岁.
- 评估包括认知,运动功能,行为和父母填写的调查问卷的标准化工具.
- 国家卫生登记册提供了诊断数据.
主要成果:
- 与对照组相比,EPT儿童的中度/重度NDD (37.4%),ASD (14.9%),ADHD (21.2%),DCD (29.4%) 和行为问题 (35.3%) 的比率显着更高.
- 并发症率很高,59%的EPT儿童中度/重度NDD至少有两个同时发生的疾病.
- 只有42.0%的EPT儿童没有ASD,ADHD和DCD.
结论:
- 在EPT儿童中,很大一部分在12岁时经历了NDD,ASD,ADHD,DCD和行为问题.
- 多种疾病的高患病率强调了对这一群体所需的护理的复杂性.
- 多学科的后续对应EPT幸存者所面临的多方面的挑战至关重要.
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