Jove
Visualize
联系我们
JoVE
x logofacebook logolinkedin logoyoutube logo
关于 JoVE
概览领导团队博客JoVE 帮助中心
作者
出版流程编辑委员会范围与政策同行评审常见问题投稿
图书馆员
用户评价订阅访问资源图书馆顾问委员会常见问题
研究
JoVE JournalMethods CollectionsJoVE Encyclopedia of Experiments存档
教育
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab Manual教师资源中心教师网站
使用条款与条件
隐私政策
政策

相关概念视频

Self-Awareness and Its Effects01:21

Self-Awareness and Its Effects

316
Self-awareness is a psychological state in which the individual becomes the focal point of their attention. This inward focus transforms the self into an object of contemplation and assessment, influencing how individuals perceive their actions and their alignment with personal and societal standards.Triggers and Contexts for Self-AwarenessSelf-awareness can be activated by external stimuli that make individuals visually or audibly aware of themselves, such as mirrors, cameras, or recordings.
316
Altered States of Awareness01:06

Altered States of Awareness

1.1K
Altered states of consciousness represent significant deviations from one's normal mental state. These deviations can range from subtle changes in awareness to profound transformations in perception, thought processes, and sensory experiences. Altered states of consciousness can be triggered by various factors, including drug use, meditation, hypnosis, illness, or even intense fatigue.
The ingestion of substances like stimulants or hallucinogens leads to chemical alterations in the brain...
1.1K
Subconsciousness and No Awareness01:15

Subconsciousness and No Awareness

713
The concept of subconscious awareness refers to the processing of information below the level of conscious thought, which significantly influences both behaviors and decisions. It is also known as waking subconscious awareness. This complex level of cognition operates without the direct awareness of the individual, facilitating rapid and simultaneous handling of multiple information streams.
An illustrative example of subconscious processing is its role in problem-solving. Often, individuals...
713
Reinforcement01:23

Reinforcement

931
Positive and negative reinforcement are key concepts in operant conditioning, a learning process where the consequences of a behavior affect the likelihood of that behavior being repeated.
Positive reinforcement occurs when a behavior is followed by the presentation of a rewarding stimulus, increasing the frequency of that behavior. For example:
931
High-Level and Low-Level Awareness01:19

High-Level and Low-Level Awareness

779
Controlled processes in human consciousness represent high-alert mental states where individuals deliberately focus their attention on achieving specific goals. Controlled processes can be seen in situations like mastering new technology, where a person might become so absorbed that they ignore surrounding distractions. Such processes involve selective attention, requiring one to concentrate on particular elements of experience while disregarding others. These are governed by executive...
779
Corrosion of Reinforcement01:27

Corrosion of Reinforcement

583
The corrosion of steel reinforcement within concrete is a process influenced by the material's inherent properties and external factors. The high pH level of around 13, provided by calcium hydroxide present in concrete, initially protects the steel reinforcement by promoting the formation of a passive iron oxide layer on its surface.
However, over time and under certain conditions like carbonation, chloride ingress, and cracking this protective state can be compromised. Steel has areas with...
583

您也可能阅读

相关文章

通过共同作者、期刊和引用图与本文相关的文章。

排序
Same author

Diagnostic performance of adenosine deaminase activity in pleural fluid in tuberculous pleural effusion and relevant factors: a single-center experience with 1,491 consecutive patients.

BMC pulmonary medicine·2025
Same author

Gradient 3D printed PEEK with nano-coating facilitates rapid manufacturing with dual enhanced osteogenic and anti-bacterial property.

Materials today. Bio·2025
Same author

Tunable Work Functions in Plasmonic Metals.

Nanomaterials (Basel, Switzerland)·2025
Same author

Intra- and intermuscular shear wave speed distributions in the human hamstrings during isometric and eccentric contractions.

European journal of applied physiology·2025
Same author

High-Abundance Heterotrophic Bacteria Inhabit the 85° E Hydrothermal Plume of the Explosive Volcanic Zone at Gakkel Ridge, Arctic Ocean.

Biology·2025
Same author

Quantitative analysis of disc-condyle movement following disc repositioning operation by arthroscopic for Bi-ADD patients.

Journal of stomatology, oral and maxillofacial surgery·2025

相关实验视频

Updated: Feb 6, 2026

Author Spotlight: Advancing Alzheimer's Research – Exploring Early Detection and Multi-Omics Approaches
09:47

Author Spotlight: Advancing Alzheimer's Research – Exploring Early Detection and Multi-Omics Approaches

Published on: December 15, 2023

1.9K

MsTargetPeaker:一种质量意识的深度强化学习方法,用于在向蛋白质组中识别峰值.

Chi Yang1, Yung-Chin Hsiao2, Chi-Ching Lee3

  • 1Molecular Medicine Research Center, Chang Gung University, Taoyuan, Taiwan.

Molecular & cellular proteomics : MCP
|February 4, 2026
PubMed
概括

MsTargetPeaker使用强化学习用于针对性质谱仪中的自动化峰值识别. 这种质量意识的方法提高了定量精度,并为手动选提供了诊断报告.

更多相关视频

Author Spotlight: AI-Driven Trypanosome Species Detection from Microscopic Images
08:20

Author Spotlight: AI-Driven Trypanosome Species Detection from Microscopic Images

Published on: October 27, 2023

2.6K
Deep Proteome Profiling by Isobaric Labeling, Extensive Liquid Chromatography, Mass Spectrometry, and Software-assisted Quantification
10:37

Deep Proteome Profiling by Isobaric Labeling, Extensive Liquid Chromatography, Mass Spectrometry, and Software-assisted Quantification

Published on: November 15, 2017

12.8K

相关实验视频

Last Updated: Feb 6, 2026

Author Spotlight: Advancing Alzheimer's Research – Exploring Early Detection and Multi-Omics Approaches
09:47

Author Spotlight: Advancing Alzheimer's Research – Exploring Early Detection and Multi-Omics Approaches

Published on: December 15, 2023

1.9K
Author Spotlight: AI-Driven Trypanosome Species Detection from Microscopic Images
08:20

Author Spotlight: AI-Driven Trypanosome Species Detection from Microscopic Images

Published on: October 27, 2023

2.6K
Deep Proteome Profiling by Isobaric Labeling, Extensive Liquid Chromatography, Mass Spectrometry, and Software-assisted Quantification
10:37

Deep Proteome Profiling by Isobaric Labeling, Extensive Liquid Chromatography, Mass Spectrometry, and Software-assisted Quantification

Published on: November 15, 2017

12.8K

科学领域:

  • 蛋白质组学是指蛋白质组学.
  • 分析化学 分析化学
  • 生物技术是生物技术.

背景情况:

  • 目标质谱学需要通过染色体峰值集成进行精确的化量化.
  • 由于噪音和干扰,自动峰值识别对低丰度具有挑战性.
  • 目前的方法使用单独的监督学习模型来选择峰值和质量控制,限制了改进.

研究的目的:

  • 开发一种以质量为基础的搜索程序,用于在向蛋白质组学中进行可靠的峰值识别.
  • 为了提高质谱数据中质量定量的精度和准确性.
  • 为高效的手动治疗提供可解释的诊断报告.

主要方法:

  • 实施了一个强化学习代理来指导蒙特卡洛树搜索进行染色体探索.
  • 开发了一个定制的奖励功能,用于在搜索过程中动态的高峰质量评估.
  • 纳入交叉样本共识配置文件,以更好地识别模两可的信号.

主要成果:

  • MsTargetPeaker有效地识别目标峰值,同时最大限度地减少干扰.
  • 动态质量评估可以准确和稳定地确定峰值边界.
  • 该方法提高了针对性蛋白质组的峰值质量和量化精度.

结论:

  • MsTargetPeaker为针对性蛋白质组学的自动化峰值识别提供了一个实用的进步.
  • 质量意识的方法提高了质量定量的稳定性和精度.
  • 生成的诊断报告有助于有效的手动审查和数据质量评估.