数字干预对抑郁症状自我管理的影响:MENTINA试验 - 一项随机对照并行组试验的研究协议
Maria Faurholt-Jepsen1,2, Malene Schwarz Dyreholt3, Natacha Blauenfeldt Kyster3
1CADIC, Copenhagen Psychiatric Center, Hellerup, Denmark maria.faurholtjepsen@regionh.dk.
BMJ open
|February 4, 2026
概括
这项研究调查了智能手机监控与反是否可以改善抑郁症症状. 结果将为数字心理健康自我管理策略提供信息.
科学领域:
- 数字心理健康数字心理健康
- 临床心理学 临床心理学
- 移动卫生干预措施 移动卫生干预
背景情况:
- 抑郁症和亚诊断综合征是常见的,导致严重的痛苦和减少预期寿命.
- 对护理的有限获取需要加强抑郁症状患者的自我管理策略.
- 智能手机可以通过持续的症状监测来提高自我管理的潜力.
研究的目的:
- 评估每日基于智能手机的自动反监测与单独的结果评估相比在改善抑郁症状方面的有效性.
- 评估干预对12个月内其他临床相关结果的影响.
- 加强患有抑郁症状的个体的自我管理专业知识.
主要方法:
- 一个多中心随机对照并行组试验 (MENTINA) 涉及目前或过去患有抑郁症的参与者.
- 随机化为每日智能手机监控与反或仅仅对智能手机结果的评估.
- 主要结局:患者健康问卷9项 (PHQ-9) 在12个月内每两周测量一次. 二次结果包括生活质量,焦虑和缓解率.
主要成果:
- 该试验正在进行中,目前已包括115名参与者,目标是总共660名参与者.
- 主要结局是PHQ-9分数在12个月的变化.
- 将评估多个次要结果,包括生活质量,焦虑和缓解率.
结论:
- 该MENTINA试验将提供证据,以智能手机为基础的干预对抑郁症自我管理的有效性.
- 调查结果将为数字心理健康工具的开发和实施提供信息.
- 该研究旨在改善抑郁症状患者的可访问性和结果.
相关概念视频
01:11Clinical Trials: Overview
5.0K
Clinical development focuses on how the drug will interact with the human body and encompasses four key phases of clinical trials, each serving a specific purpose in assessing the safety and effectiveness of new drugs. These phases overlap and build upon one another. Phase I involves a small group of healthy volunteers (typically 20-80 individuals) or, in cases where significant toxicity is expected, patients with the targeted disease, such as cancer or AIDS. The volunteers are tested for...
5.0K
01:12Trial and Error and Algorithm
424
A problem-solving strategy is a plan of action used to find a solution. Different strategies have distinct action plans. Trial and error involves trying different solutions until one works. For instance, to fix a broken printer, you might check ink levels, ensure the paper tray isn't jammed, and verify the printer's connection to your laptop. This method can be time-consuming but is commonly used. Thomas Edison, for example, used trial and error to find a suitable filament for the light...
424
01:16Clinical Trials
10.8K
Clinical trials are prospective experimental studies conducted on humans to determine the safety and efficacy of treatments, drugs, diet methods, and medical devices. Using statistics in clinical trials enables researchers to derive reasonable and accurate conclusions from the collected data, allowing them to make wise decisions in uncertain situations. In medical research, statistical methods are crucial for preventing errors and bias.
There are four phases in a clinical trial. A phase one...
There are four phases in a clinical trial. A phase one...
10.8K
01:28Pleural Effusion II: Symptoms and Management
794
Pleural Effusion Overview
A pleural effusion is the abnormal collection of fluid between the parietal and visceral pleura layers of tissue that form the lining of the lungs and chest cavity. It can occur independently or due to surrounding parenchymal diseases, such as infection, malignancy, or inflammatory conditions.
Clinical Manifestations:
A pleural effusion is the abnormal collection of fluid between the parietal and visceral pleura layers of tissue that form the lining of the lungs and chest cavity. It can occur independently or due to surrounding parenchymal diseases, such as infection, malignancy, or inflammatory conditions.
Clinical Manifestations:
794
01:12Statistical Software for Data Analysis and Clinical Trials
1.6K
Statistical software is pivotal in data analysis and clinical trials by providing tools to analyze data, draw conclusions, and make predictions. These software packages range from simple data management applications to complex analytical platforms, supporting various statistical tests, models, and simulation techniques. Their significance lies in their ability to handle vast amounts of data with precision and efficiency, enabling researchers to validate hypotheses, identify trends, and make...
1.6K
01:05Long-term Depression
33.3K
Long-term depression, or LTD, is one of the ways by which synaptic plasticity—changes in the strength of chemical synapses—can occur in the brain. LTD is the process of synaptic weakening that occurs over time between pre and postsynaptic neuronal connections. The synaptic weakening of LTD works in opposition to synaptic strengthening by long-term potentiation (LTP) and together are the main mechanisms that underlie learning and memory.
33.3K