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Indicators02:39

Indicators

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Certain organic substances change color in dilute solution when the hydronium ion concentration reaches a particular value. For example, phenolphthalein is a colorless substance in any aqueous solution with a hydronium ion concentration greater than 5.0 × 10−9 M (pH < 8.3). In more basic solutions where the hydronium ion concentration is less than 5.0 × 10−9 M (pH > 8.3), it is red or pink. Substances such as phenolphthalein, which can be used to determine the pH of a solution, are...
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Pericarditis II: Clinical Features and Diagnostic Tests01:19

Pericarditis II: Clinical Features and Diagnostic Tests

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Pericarditis is distinguished by inflammation of the pericardium, the fibrous sac that encases the heart. It can be acute, lasting less than six weeks, or chronic, persisting for over three months. Understanding its clinical manifestations and diagnostic findings is crucial for timely and effective management.Clinical ManifestationsWhile pericarditis can be asymptomatic, it usually presents with characteristic symptoms such as:Chest Pain: The most characteristic symptom of pericarditis is chest...
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Atherosclerosis II: Clinical Manifestations and Diagnostic Tests01:27

Atherosclerosis II: Clinical Manifestations and Diagnostic Tests

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Atherosclerosis is a progressive disorder that leads to the thickening and narrowing of arterial walls due to plaque buildup. This condition can cause various symptoms depending on the arteries affected:Coronary Artery Disease (CAD): This condition affects the coronary arteries and may lead to chest pain (angina), shortness of breath (dyspnea), heart attacks, and other heart disease symptoms.Cerebrovascular Disease: This affects blood flow to the brain, causing transient ischemic attacks (TIAs)...
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Aneurysm II: Clinical Manifestations and Diagnostic Studies01:21

Aneurysm II: Clinical Manifestations and Diagnostic Studies

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Thoracic, aortic arch and abdominal aneurysms are significant vascular conditions that can present with various clinical manifestations and lead to serious complications. Understanding these manifestations and the appropriate diagnostic studies is essential for effective management and treatment.Thoracic Aortic AneurysmsThoracic aortic aneurysms often remain asymptomatic until they reach a size that impinges on adjacent structures. They typically cause deep, diffuse chest pain that radiates to...
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Myocarditis II: Clinical Features and Diagnostic Tests01:27

Myocarditis II: Clinical Features and Diagnostic Tests

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Myocarditis is an inflammation of the heart muscle. The symptoms vary widely, encompassing asymptomatic presentations to severe, acute manifestations.Clinical PresentationAsymptomatic cases: In some instances, myocarditis may be asymptomatic, with the infection resolving without intervention. These cases often go undetected unless discovered incidentally through diagnostic imaging or tests conducted for other reasons.General Early Symptoms: Early symptoms of myocarditis are non-specific and can...
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Mitral Regurgitation II: Clinical Features and Diagnostic Tests01:23

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Mitral regurgitation (MR) is a valvular heart disorder in which the mitral valve fails to close tightly, allowing blood to leak backward into the heart. Understanding the clinical manifestations, assessment, diagnostic findings, and medical management of MR is crucial to effectively managing affected patients.Clinical Manifestations of Mitral RegurgitationMitral regurgitation can be acute or chronic, each presenting differently and requiring different approaches:1. Acute Mitral...
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相关实验视频

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基于临床指示的CT诊断参考水平:系统性审查

Abdul Alim1,2, Sook Sam Leong3,4, Ann Erynna Lema Thomas Sudin1

  • 1Center for Medical Imaging Studies, Universiti Teknologi MARA, Puncak Alam, Selangor, Malaysia.

BMJ open
|February 4, 2026
PubMed
概括

在CT中,基于临床指示 (NDRLci) 的国家诊断参考水平差异很大. 标准化NDRLci开发对于改善全球CT剂量可比性至关重要.

关键词:
计算机断层扫描 (CT) 是一种计算机断层扫描.诊断成像 诊断成像 诊断成像放射学和成像学 放射学和成像学

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科学领域:

  • 放射物理学和医学成像学
  • 诊断成像和辐射保护技术

背景情况:

  • 基于临床指示 (NDRLci) 的国家诊断参考水平在全球范围内越来越多地采用ICRP 2017年建议.
  • 在NDRLci实践中存在显著差异,需要进行比较分析和确定影响因素.

研究的目的:

  • 为了比较CT检查的国际NDRLci实践.
  • 为了确定影响不同临床适应症的NDRLci值的因素.
  • 为制定标准化的NDRLci.提出基于证据的建议.

主要方法:

  • 对1996年至2025年间发表的研究进行系统的文献综述.
  • 在PubMed,科学网和Scopus进行的搜索.
  • 遵守PRISMA指南和使用Joanna Briggs研究所工具进行批判性评估.

主要成果:

  • 纳入了11项研究,分析了7个解剖区域的25个临床征兆.
  • 在严重创伤 (3830 mGy cm) 中全身CT报告的最高NDRLci (DLP),在鼻炎 (70 mGy cm) 中最低.
  • 观察到相同临床适应症的显著剂量差异.

结论:

  • 诸如CT技术,协议参数和患者特征等因素影响NDRLci.
  • 标准化和优化CT协议至关重要.
  • 国际标准化NDRLci开发对于全球可比性至关重要.