加纳抗微生物药物耐药性的可归因社会成本:以社会人口群体为重点的微型模拟研究
Ama Pokuaa Fenny1, Evans Otieku2,3, Robert Ofori Amoah3
1Institute of Statistical, Social and Economic Research, University of Ghana, Legon, Ghana.
BMJ open
|February 4, 2026
概括
在加纳,抗菌素耐药性 (AMR) 每年花费大约4.35亿美元,带来显著的生产力损失. 消除AMR可能会带来巨大的社会成本节约,突出需要紧急减缓努力.
科学领域:
- 公共卫生 公共卫生
- 卫生经济学 卫生经济学
- 流行病学 流行病学
背景情况:
- 抗菌素耐药性 (AMR) 构成了全球健康的重大威胁.
- 量化AMR的经济负担对于为公共卫生政策和干预措施提供信息至关重要.
研究的目的:
- 预测加纳AMR的社会成本.
- 为了估计潜在的成本节约,如果AMR在加纳被消除.
主要方法:
- 使用加纳国家数据 (2021年6月至2023年12月) 进行了微模拟分析.
- 该模型包括人口统计,感染流行病学,医疗保健成本和劳动力市场数据.
- 社会成本是从社会角度计算的,从7年的时间来看,考虑了人口增长和折扣率等因素.
主要成果:
- 预计每年将有近78,000例AMR感染和大约6,300例可归因死亡.
- 据估计,AMR的年平均社会成本为4.35亿美元.
- 死亡率造成的生产力损失是最大的成本组成部分 (40.6%),其次是医疗保健提供者成本 (24.1%) 和患者的直接医疗成本 (22.4%).
- 5岁以下的儿童和60岁以上的成年人承担了AMR成本的不成比例份额.
结论:
- 非洲抗药性对加纳的社会成本影响是巨大的.
- 需要协同的社会努力来缓解AMR生物体的发展和传播.
- 消除AMR可以为加纳带来重大的经济效益.
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