200 J-第一,固定升级的两相电动心脏转换对于心房动>48小时在急诊室:一个单中心的回顾性观察性研究
Jakub Nozewski1, Zbigniew Siudak2, Barbra E Backus3
1Emergency Medicine, Nicolaus Copernicus University in Torun, Bydgoszcz, Poland jbnoz@wp.pl.
Open heart
|February 4, 2026
概括
对于心房动 (AF) 的200 J-first电动心脏转换方案显示了高的成功率. 这种方法,使用手动和坚定的压力,在急诊室设置中取得了很好的结果.
科学领域:
- 心脏病学 心脏病学
- 紧急医疗 紧急医疗
- 电子生理学 电子生理学
背景情况:
- 目前的指导方针允许在持续超过48小时的心房动 (AF) 中,双相电心转动 (ECV) 最大360 J.
- 之前的研究表明,与低升级协议相比,360 J的成功率更高,通常使用粘合和特定定位.
- 这项研究研究了200 J-first,固定升级的ECV协议,在急诊室使用标准化技术.
研究的目的:
- 评估200 J-first,固定升级双相ECV协议的疗效和安全性,用于症状AF>48小时.
- 评估200 J的第一冲击成功率和累积疗效.
- 为了将结果与历史360 J-first队伍进行比较.
主要方法:
- 对374名成人患者进行了回顾性观察性研究,这些患者在AF>48小时 (2019-2021) 接受了选择性ECV.
- 程序使用手持,在深度镇静下,在前侧位置施加坚定的胸部压力.
- 采用了预定义的200→300→360 J的能量序列,主要结果是通过心电图在120分钟内记录鼻节律 (SR).
主要成果:
- 恢复SR的主要结果在97.3%的患者中实现.
- 在200 J的第一冲击成功率为88.0%,在少数情况下需要升级到300 J或360 J.
- 仅记录了两个轻微的不良事件 (0.5%),没有严重的不良事件.
结论:
- 一个使用标准化技术的200 J-first,固定升级的双相ECV协议在ED中对AF>48小时非常有效.
- 这种方法可以实现高的第一冲击和累积疗效,而不需要常规的药理学辅助.
- 这些发现支持通过多中心随机试验进行进一步的调查,比较200个J-first与360个J-first协议.
相关概念视频
Amyloid Fibrils
12.0K
Amyloid fibrils are aggregates of misfolded proteins. Under most circumstances, misfolded proteins are either refolded by chaperone proteins or degraded by the proteasome. However, in the case of a mutation or a disease, these proteins can accumulate to form large clusters and often further assemble to form elongated fibers, called fibrils.
Amyloid deposits were observed as early as 1639 in the liver and the spleen. In 1854, Rudolph Virchow performed iodine staining,...
Amyloid deposits were observed as early as 1639 in the liver and the spleen. In 1854, Rudolph Virchow performed iodine staining,...
12.0K
Amyloid Fibrils
6.4K
6.4K
Observational Studies
11.1K
Observational studies are a type of analytical study where researchers observe events without any interventions. In other words, the researcher does not influence the response variable or the experiment's outcome.
There are three types of observational studies – Prospective, retrospective, and cross-sectional.
Prospective Study
Prospective studies, also known as longitudinal or cohort studies, are carried out by collecting future data from groups sharing similar characteristics. One...
There are three types of observational studies – Prospective, retrospective, and cross-sectional.
Prospective Study
Prospective studies, also known as longitudinal or cohort studies, are carried out by collecting future data from groups sharing similar characteristics. One...
11.1K
Emerging Adulthood
700
Jeffrey Arnett's concept of emerging adulthood offers a framework to understand the unique developmental stage between adolescence and full-fledged adulthood, generally from ages 18 to 25. This period is marked by extensive exploration and shifts in identity, relationships, and career choices, a process known in psychology as role experimentation. Emerging adulthood reflects the evolving cultural expectations surrounding adulthood and the dynamic process of personal transformation during...
700
Holter Monitor: 24-Hour Monitoring
2.6K
Holter monitoring is a continuous electrocardiography (ECG) recording that tracks the heart's electrical activity over an extended period, generally 24 to 48 hours. This noninvasive diagnostic tool detects irregular heart rhythms that may not be captured during a standard ECG performed in a clinical setting.DeviceThe Holter monitor is a portable, small device connected to several electrodes on the patient's chest. These electrodes detect the heart's electrical signals and transmit them to the...
2.6K
Fibril-associated Collagen
3.4K
Fibril-associated collagens are a type of collagens present in the extracellular matrix with interrupted triple helices or FACIT (Fibril-associated collagens interrupted triple-helices). FACIT help connect and attach the collagen fibrils with each other as well as with other proteins of the extracellular matrix.
For example, the type II collagen fibrils in cartilage have covalently bound type IX fibril-associated collagens at regular intervals. Other types of fibril-associated collagens are...
For example, the type II collagen fibrils in cartilage have covalently bound type IX fibril-associated collagens at regular intervals. Other types of fibril-associated collagens are...
3.4K


